Adaptive Biotechnologies

ADPT · NASDAQ

$24.42+$0.47 (+1.96%)TodayMarket closed ·
Prev close $23.95

ADPT analyst rating

BuyConsensus of 8 analysts over the last 12 months. 88% rate it a buy.
  • Strong buy0
  • Buy7
  • Hold1
  • Underperform0
  • Sell0

12-month price target · 10 analysts

Average $28.05 (+14.9% upside)

Low
$21.21
Now
$24.42
High
$36.75

Upgrades and downgrades

The latest rating actions, newest first

ADPT analyst upgrades, downgrades and rating actions
FirmDateActionRating
TD CowenOct 13, 2026MaintainsBuy
Morgan StanleyOct 13, 2026MaintainsEqual-Weight
GuggenheimOct 1, 2026MaintainsBuy
Goldman SachsSep 29, 2026InitiatesBuy
BTIGSep 22, 2026MaintainsBuy
Piper SandlerAug 4, 2026MaintainsOverweight
Morgan StanleyJul 30, 2026MaintainsEqual-Weight
TD CowenJul 30, 2026MaintainsBuy
GuggenheimJul 30, 2026MaintainsBuy
BTIGJul 30, 2026MaintainsBuy

The case for and against

Updated Oct 16, 2026

Bull case

Adaptive Biotechnologies is viewed positively because NCCN’s updated multiple myeloma guidelines explicitly name clonoSEQ, expand MRD testing timepoints, and create a more standardized framework that could lift utilization from the current run-rate. Strong execution in the core MRD business also supports the thesis, with Q2’26 MRD revenue guidance raised to $268M-$278M, volume growth of 43% in Q2’26, sequencing gross margins at 71%, and ASPs already reaching $1,382 per test with a path to $1,700-$1,800. The outlook is further strengthened by rising blood-based adoption at 51% of volumes, growing EMR integrations, a 2026 business separation plan, and a broad clinical-trial opportunity after the positive 12-0 ODAC vote.

Bear case

Adaptive Biotechnologies is viewed negatively because its core business still depends heavily on clonoSEQ and the MRD segment, yet the company faces clear execution risk from slower-than-expected customer adoption, reimbursement and clinical guideline hurdles, and new competition. The excerpts also highlight broader sector headwinds such as reduced research and development budgets, delayed hospital purchasing, and regulatory hurdles, all of which can pressure revenue growth and keep profitability elusive. In addition, the comparison to other companies trading at premium multiples and the uncertainty around business separation by YE'26 underscore valuation and strategic risk rather than durable fundamental strength.

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