Madrigal Pharmaceuticals

MDGL · NASDAQ

$467.54+$20.45 (+4.57%)TodayMarket closed · Oct 20, 7:30 PM ET

Prev close $447.09

Who owns MDGL

Largest institutional holders, from their latest 13F filings

The 10 largest institutions hold 57.9% of MDGL’s shares.

Baker Bros. Advisors LP9.3%
RTW Investments L.P.8.6%
Janus Henderson Investors8.4%
Avoro Capital Advisors LLC8.0%
Next 6 largest institutions23.6%
All other shareholders42.1%

Top institutional holders of MDGL
Holder	Shares	% of shares	Change, last filing	Filed
Baker Bros. Advisors LP	2.14M	9.29%	+1.43K	Jun 30, 2026
RTW Investments L.P.	1.99M	8.65%	+0	Jun 30, 2026
Janus Henderson Investors	1.94M	8.40%	−82.55K	Jun 30, 2026
Avoro Capital Advisors LLC	1.83M	7.95%	+15.15K	Jun 30, 2026
Paulson & Co. Inc.	1.34M	5.81%	−52.17K	Jun 30, 2026
BlackRock Institutional Trust Company, N.A.	1.01M	4.40%	−307.65K	Jun 30, 2026
Vanguard Capital Management, LLC	835.67K	3.62%	+8.52K	Jun 30, 2026
Wellington Management Company, LLP	825.71K	3.58%	+130.76K	Jun 30, 2026
Vanguard Portfolio Management, LLC	781.73K	3.39%	−59.41K	Jun 30, 2026
SQN, L.L.C.	655.54K	2.84%	+0	Apr 21, 2026

Largest mutual fund holders

Top mutual fund holders of MDGL
Holder	Shares	% of shares	Change, last filing	Filed
Vanguard Total Stock Market Index Fund	586.88K	2.54%	+1.77K	Jul 31, 2026
Vanguard Health Care Fund	521.93K	2.26%	+77.79K	Jun 30, 2026
Vanguard Small-Cap Index Fund	424.12K	1.84%	+1.08K	Jul 31, 2026
Janus Henderson Forty Fund	338.60K	1.47%	−77.23K	Jun 30, 2026
Polar Capital Biotechnology Fund	273.99K	1.19%	+42.97K	Jul 31, 2026

Insider trades

Form 4 filings by officers, directors and large holders

Over the last 6 months, insiders sold $11.83M (49 trades) of MDGL on the open market, with no buys.

Latest MDGL insider transactions
Insider	Date	Type	Shares	Price	Value
Sibold William John	Sep 11, 2026	Sale	120	$546.38	$65.57K
Sibold William John	Sep 11, 2026	Sale	761	$544.83	$414.62K
Sibold William John	Sep 11, 2026	Sale	1.54K	$544.02	$837.25K
Sibold William John	Sep 11, 2026	Sale	1.20K	$542.60	$652.21K
Sibold William John	Sep 11, 2026	Sale	368	$541.64	$199.32K
Sibold William John	Sep 11, 2026	Sale	687	$540.59	$371.38K
Sibold William John	Sep 11, 2026	Sale	160	$537.62	$86.02K
Sibold William John	Sep 11, 2026	Sale	218	$535.94	$116.84K
Sibold William John	Sep 11, 2026	Sale	106	$534.06	$56.61K
Sibold William John	Sep 11, 2026	Sale	60	$533.09	$31.99K

Short interest

Settled Sep 30, 2026

Shares short: 2.40M
Days to cover: 9.78
% of shares outstanding: 10.39%
Average daily volume: 245.00K
Change since last report: +6.3%

Information on this page is provided for informational purposes only and is not a recommendation to buy, sell or hold any security. Investing involves risk, including possible loss of principal. Market data is delayed at least 15 minutes and is provided without warranty. Analyst ratings, price targets and company data come from third-party sources. Past performance does not guarantee future results.