Amylyx Pharmaceuticals

AMLX · NASDAQ

$28.77+$1.44 (+5.27%)TodayMarket closed ·
Prev close $27.33

Who owns AMLX

Largest institutional holders, from their latest 13F filings

The 10 largest institutions hold 57.7% of AMLX’s shares.

  • Fidelity Management & Research Company LLC13.5%
  • Perceptive Advisors LLC7.5%
  • BlackRock Institutional Trust Company, N.A.6.7%
  • TCG Crossover Management, LLC5.6%
  • Next 6 largest institutions24.3%
  • All other shareholders42.3%
Top institutional holders of AMLX
HolderShares% of shares
Fidelity Management & Research Company LLC15.04M13.53%
Perceptive Advisors LLC8.33M7.50%
BlackRock Institutional Trust Company, N.A.7.48M6.73%
TCG Crossover Management, LLC6.24M5.62%
Commodore Capital LP5.65M5.08%
Janus Henderson Investors5.24M4.71%
Saturn V Capital Management LP4.62M4.16%
Vanguard Capital Management, LLC4.22M3.80%
Cohen (Joshua Barry)3.64M3.28%
Klee (Justin B)3.64M3.28%

Largest mutual fund holders

Top mutual fund holders of AMLX
HolderShares% of shares
Vanguard Total Stock Market Index Fund3.17M2.85%
Fidelity Advisor Biotechnology Fund2.43M2.19%
iShares Russell 2000 ETF2.36M2.13%
Fidelity Small Cap Growth Fund2.12M1.90%
Eventide Healthcare & Life Sciences Fund1.51M1.36%

Insider trades

Form 4 filings by officers, directors and large holders

Over the last 6 months, insiders bought $51.34K (1 trade) and sold $4.31M (13 trades) of AMLX on the open market.

Latest AMLX insider transactions
InsiderTypeSharesValue
MILNE GEORGE M JRSale30.00K$830.90K
Mazzariello GinaSale11$367
Mazzariello GinaSale9.53K$309.14K
Cohen Joshua BSale919$30.46K
Cohen Joshua BSale29.55K$950.04K
Klee Justin B.Sale1.44K$47.71K
Klee Justin B.Sale29.02K$932.55K
Bedrosian Camille LSale2.08K$68.86K
Bedrosian Camille LSale7.95K$256.00K
FRATES JAMES MSale1.04K$34.63K

Short interest

Settled Sep 30, 2026

Shares short
12.67M
Days to cover
9.16
% of shares outstanding
11.39%
Average daily volume
1.38M
Change since last report
−6.3%

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