Karyopharm Therapeutics

KPTI · NASDAQ

$0.3586+$0.0126 (+3.64%)TodayMarket closed ·
Prev close $0.346

Who owns KPTI

Largest institutional holders, from their latest 13F filings

The 10 largest institutions hold 52.8% of KPTI’s shares.

  • RA Capital Management, LP8.5%
  • Adage Capital Management, L.P.6.7%
  • Acorn Capital Advisors, LLC6.7%
  • Goldman Sachs & Co. LLC6.1%
  • Next 6 largest institutions24.8%
  • All other shareholders47.2%
Top institutional holders of KPTI
HolderShares% of shares
RA Capital Management, LP1.92M8.46%
Adage Capital Management, L.P.1.52M6.71%
Acorn Capital Advisors, LLC1.52M6.70%
Goldman Sachs & Co. LLC1.39M6.13%
BlackRock Institutional Trust Company, N.A.1.23M5.42%
Vanguard Capital Management, LLC958.98K4.23%
Catalio Capital Management, LP940.86K4.15%
Avidity Partners Management LP924.49K4.08%
T. Rowe Price Investment Management, Inc.786.31K3.47%
J. Wood Capital Advisors LLC784.80K3.46%

Largest mutual fund holders

Top mutual fund holders of KPTI
HolderShares% of shares
Vanguard Total Stock Market Index Fund677.73K2.99%
iShares Russell 2000 ETF488.18K2.15%
T. Rowe Price Small Cap Value Fund435.07K1.92%
Vanguard Extended Market Index Fund263.08K1.16%
Fidelity Small Cap Index Fund214.60K0.95%

Insider trades

Form 4 filings by officers, directors and large holders

Over the last 6 months, insiders sold $40.59K (10 trades) of KPTI on the open market, with no buys.

Latest KPTI insider transactions
InsiderTypeSharesValue
Abate KristinSale378$450
Abate KristinSale19$38
Poulton StuartSale189$1.34K
Su ZhenAward15.51K—
Oliger Christy J.Award15.51K—
Schor ChenAward15.51K—
Greene Barry EAward15.51K—
PAKIANATHAN DEEPIKAAward15.51K—
BOHLIN GAREN GAward15.51K—
Poulton StuartSale403$3.83K

Short interest

Settled Sep 30, 2026

Shares short
6.06M
Days to cover
4.79
% of shares outstanding
26.73%
Average daily volume
1.26M
Change since last report
−23.0%

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