Spero Therapeutics

SPRO · NASDAQ

$1.22+$0.10 (+8.93%)TodayMarket closed ·
Prev close $1.12

Who owns SPRO

Largest institutional holders, from their latest 13F filings

The 10 largest institutions hold 31.6% of SPRO’s shares.

  • GSK plc15.9%
  • Pfizer Inc.4.1%
  • Vanguard Capital Management, LLC3.5%
  • Renaissance Technologies LLC1.6%
  • Next 6 largest institutions6.5%
  • All other shareholders68.4%
Top institutional holders of SPRO
HolderShares% of shares
GSK plc9.19M15.87%
Pfizer Inc.2.36M4.08%
Vanguard Capital Management, LLC2.04M3.52%
Renaissance Technologies LLC947.90K1.64%
Alphabet, Inc.889.98K1.54%
Susquehanna International Group, LLP759.29K1.31%
BlackRock Institutional Trust Company, N.A.583.21K1.01%
Geode Capital Management, L.L.C.566.33K0.98%
ClariVest Asset Management LLC518.64K0.90%
Florida State Board of Administration462.19K0.80%

Largest mutual fund holders

Top mutual fund holders of SPRO
HolderShares% of shares
Vanguard Total Stock Market Index Fund1.40M2.41%
Vanguard Extended Market Index Fund593.25K1.02%
Florida State Board Administration Fund462.19K0.80%
Fidelity Extended Market Index Fund248.94K0.43%
iShares Micro-Cap ETF153.19K0.26%

Insider trades

Form 4 filings by officers, directors and large holders

Over the last 6 months, insiders sold $63.35K (1 trade) of SPRO on the open market, with no buys.

Latest SPRO insider transactions
InsiderTypeSharesValue
Zack DebraAward324.68K—
Zack DebraAward162.31K—
Tregoning KathleenAward20.00K—
Tregoning KathleenAward10.00K—
Smith CynthiaAward20.00K—
Smith CynthiaAward10.00K—
Jackson Scott ThomasAward20.00K—
Jackson Scott ThomasAward10.00K—
VINK PATRICK V.J.J.Award20.00K—
VINK PATRICK V.J.J.Award10.00K—

Short interest

Settled Sep 30, 2026

Shares short
794.51K
Days to cover
1.00
% of shares outstanding
1.37%
Average daily volume
1.14M
Change since last report
−18.6%

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